Purpose: To determine whether amniotic membrane homogenate is as effective in healing corneal damage as amniotic membrane transplantation in a rabbit model.
Method: The rabbits were divided into three groups. The cornea of one eye in each rabbit was incised resulting in a defect of approximately 8 mm in diameter. Amniotic membrane transplantation was performed in the first group, and amnion homogenate was administered four times a day in the second group. The third group was the control group.
Results: There were no differences in the diameter of the defects and the rate of corneal growth between the amnion transplant group and the amnion homogenate group.
Conclusion: Amnion homogenate is as effective as transplanted amniotic membrane in promoting corneal healing in a rabbit model.
© 2011 The Authors. Acta Ophthalmologica © 2011 Acta Ophthalmologica Scandinavica Foundation.