Small dose... big poison

Aust Fam Physician. 2010 Nov;39(11):826-33.

Abstract

Background: It is not possible to identify all toxic substances in a single journal article. However, there are some exposures that in small doses are potentially fatal. Many of these exposures are particularly toxic to children. Using data from poison control centres, it is possible to recognise this group of exposures.

Objective: This article provides information to assist the general practitioner to identify potential toxic substance exposures in children.

Discussion: In this article the authors report the signs and symptoms of toxic exposures and identify the time of onset. Where clear recommendations on the period of observation and known fatal dose are available, these are provided. We do not discuss management or disposition, and advise readers to contact the Poison Information Service or a toxicologist for this advice.

Publication types

  • Review

MeSH terms

  • Adrenergic beta-Antagonists / poisoning
  • Anti-Arrhythmia Agents / poisoning
  • Antidepressive Agents, Tricyclic / poisoning
  • Antimalarials / poisoning
  • Calcium Channel Blockers / poisoning
  • Child
  • Clonidine / poisoning
  • Flecainide / poisoning
  • General Practitioners*
  • Household Products / poisoning
  • Humans
  • Hypoglycemic Agents / poisoning
  • Pediatrics*
  • Poison Control Centers*
  • Poisons*
  • Prescription Drugs / poisoning
  • Primary Health Care*
  • Time Factors

Substances

  • Adrenergic beta-Antagonists
  • Anti-Arrhythmia Agents
  • Antidepressive Agents, Tricyclic
  • Antimalarials
  • Calcium Channel Blockers
  • Hypoglycemic Agents
  • Poisons
  • Prescription Drugs
  • Flecainide
  • Clonidine