Novel HIV-1 recombinant forms in antenatal cohort, Montreal, Quebec, Canada

Emerg Infect Dis. 2011 Feb;17(2):271-4. doi: 10.3201/eid1702.100629.

Abstract

Near full-length genomes of 4 unclassified HIV-1 variants infecting patients enrolled in an antenatal cohort in Canada were obtained by sequencing. All 4 variants showed original recombination profiles, including A1/A2/J, A1/D, and A1/G/J/CRF11_cpx structures. Identification of these variants highlights the growing prevalence of unique recombinant forms of HIV-1 in North America.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Canada / epidemiology
  • Cohort Studies
  • Female
  • Genome, Viral
  • HIV Infections / diagnosis
  • HIV Infections / epidemiology*
  • HIV Infections / virology
  • HIV-1 / classification
  • HIV-1 / genetics*
  • HIV-1 / isolation & purification
  • Humans
  • Phylogeny
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis
  • Pregnancy Complications, Infectious / epidemiology*
  • Pregnancy Complications, Infectious / virology
  • Prenatal Diagnosis*
  • Prevalence
  • Quebec / epidemiology
  • Recombination, Genetic*
  • Sequence Analysis, DNA