Asymmetric total synthesis of (+)-danicalipin A

Org Lett. 2011 Mar 4;13(5):908-11. doi: 10.1021/ol1029518. Epub 2011 Feb 2.

Abstract

A convergent asymmetric total synthesis of (+)-danicalipin A is accomplished, in which two chlorinated fragments are stereoselectively joined by 1,3-dipolar coupling, leading to the confirmation of the absolute configuration of the natural product.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Lipids / chemical synthesis*
  • Lipids / chemistry
  • Molecular Structure
  • Ochromonas / chemistry
  • Stereoisomerism

Substances

  • Lipids
  • danicalipin A