Kava, the anxiolytic herb: back to basics to prevent liver injury?

Br J Clin Pharmacol. 2011 Mar;71(3):445-8. doi: 10.1111/j.1365-2125.2010.03775.x.

Abstract

The use of the anxiolytic herb kava has caused toxic liver injury in Western countries and economic problems in South Pacific Islands due to tthe regulatory ban on kava. This analysis shows poor quality of kava raw material as a cause for its toxicity and suggests preventative measures by going back to the traditional use of kava for the sake of the patients and the South Pacific economy.

MeSH terms

  • Anti-Anxiety Agents / adverse effects*
  • Chemical and Drug Induced Liver Injury / etiology*
  • Humans
  • Kava / adverse effects*
  • Liver / drug effects*
  • Pacific Islands
  • Plants, Medicinal / adverse effects*
  • Rhizome / adverse effects

Substances

  • Anti-Anxiety Agents