[Mortality trend from liver cirrhosis in Chile from 1990 to 2007]

Rev Med Chil. 2010 Oct;138(10):1253-8. Epub 2011 Jan 10.
[Article in Spanish]

Abstract

Background: There is a worldwide tendency towards a reduction in the rates of deaths due to cirrhosis. In Chile, a decrease in the number of hospital admissions due to this disease has been recorded.

Aim: To assess general characteristics and temporal evolution of liver cirrhosis mortality in Chile between 1990 and 2007.

Material and methods: National death records and population databases were reviewed. Crude and age-adjusted mortality rates for alcoholic and non-alcoholic cirrhosis were calculated, evaluating their evolution in the study period and the relative risk by gender.

Results: In the study period, 44,894 deaths caused by cirrhosis were recorded. Mortality rate was 16.6 deaths per 100,000 inhabitants. 54% of deaths were attributed to non-alcoholic cirrhosis. There was a reduction in mortality rates for both types of cirrhosis. Males accounted for 83 and 65% of deaths caused by alcoholic and non-alcoholic cirrhosis, respectively. The figures for relative risk of death were 5 and 1.9, respectively.

Conclusions: Alcoholic cirrhosis was the preponderant cause among liver cirrhosis deaths. A decrease in mortality rates was observed in the study period. Improvements in disease treatment and control could possibly explain this trend.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Chile / epidemiology
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Liver Cirrhosis / mortality*
  • Male
  • Mortality / trends
  • Prevalence
  • Risk Factors