The risk of contracting infective diseases, which may be potentially lethal, from transfused blood has led to a necessary critical review of the transfusion practice. Autologous transfusion eliminates such risk and appears as an ideal procedure for a pre-hospital donation program particularly useful in elective surgery. To determine the extent to which predeposited autologous blood is used in patients undergoing elective surgery and to assess whether predonation decreases the use of homologous blood and the demand of blood supply, the Authors studied 261 patients submitted to elective surgery from October 1986 to October 1989. In the Authors' opinion a predeposit autotransfusion program is cost-effective, practical and nondisruptive. Therefore, it should be considered as a necessary and standard medical practice by clinicians and patients.