Sternal metastasis of breast cancer: ex vivo hypothermia and reimplantation

Ann Thorac Surg. 2011 Feb;91(2):584-6. doi: 10.1016/j.athoracsur.2010.08.029.

Abstract

Breast cancer frequently metastasizes to the bone. When the sternum is involved, it usually presents as a solitary lesion. In such cases, resection is indicated, including with the intention to cure. This case report describes a technique for a complete exeresis of the sternum, ex vivo repair under hypothermia, and reimplantation. Cryosurgery is a well-known technique to resect bone metastases and was the procedure used in our patient. The follow-up after 2 years shows no evidence of tumor recurrence, with excellent results on aesthetic levels.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biopsy, Needle
  • Bone Neoplasms / diagnosis
  • Bone Neoplasms / drug therapy
  • Bone Neoplasms / pathology
  • Bone Neoplasms / secondary*
  • Breast Neoplasms / drug therapy
  • Breast Neoplasms / pathology*
  • Breast Neoplasms / surgery
  • Carcinoma, Ductal, Breast / drug therapy
  • Carcinoma, Ductal, Breast / pathology
  • Carcinoma, Ductal, Breast / secondary*
  • Carcinoma, Ductal, Breast / surgery*
  • Chemotherapy, Adjuvant
  • Cryosurgery / methods
  • Cyclophosphamide / administration & dosage
  • Doxorubicin / administration & dosage
  • Female
  • Fluorouracil / administration & dosage
  • Follow-Up Studies
  • Humans
  • Hypothermia, Induced / methods*
  • Mastectomy
  • Middle Aged
  • Neoplasm Staging
  • Radionuclide Imaging
  • Replantation / methods*
  • Sternum / diagnostic imaging
  • Sternum / pathology
  • Sternum / surgery*
  • Tamoxifen / administration & dosage

Substances

  • Tamoxifen
  • Doxorubicin
  • Cyclophosphamide
  • Fluorouracil