Phylogenetic analysis of NS5B gene of classical swine fever virus isolates indicates plausible Chinese origin of Indian subgroup 2.2 viruses

Virus Genes. 2012 Feb;44(1):104-8. doi: 10.1007/s11262-011-0572-1. Epub 2011 Jan 19.

Abstract

Twenty-three CSFV isolates recovered from field outbreaks in various parts of India during 2006-2009 were used for genetic analysis in the NS5B region (409 nts). Seventeen of these were studied earlier [16] in the 5'UTR region. Phylogenetic analysis indicated the continued dominance of subgroup 1.1 strains in the country. Detailed analysis of a subgroup 2.2 virus indicated the plausible Chinese origin of this subgroup in India and provided indirect evidence of routes of CSFV movement within South East Asia region.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • China / epidemiology
  • Classical Swine Fever / epidemiology
  • Classical Swine Fever / virology*
  • Classical Swine Fever Virus / classification*
  • Classical Swine Fever Virus / genetics
  • Classical Swine Fever Virus / isolation & purification*
  • India / epidemiology
  • Molecular Sequence Data
  • Phylogeny*
  • Swine
  • Viral Nonstructural Proteins / genetics*

Substances

  • Viral Nonstructural Proteins