Status epilepticus in fragile X syndrome

Epilepsia. 2010 Dec;51(12):2470-3. doi: 10.1111/j.1528-1167.2010.02761.x. Epub 2010 Nov 3.

Abstract

Epilepsy is frequent in fragile X syndrome (FXS), the most common cause of inherited mental retardation. Status epilepticus (SE), however, seems exceptional in FXS, particularly as an initial epileptic manifestation. To our knowledge, SE was reported in only four FXS patients. We report the clinical features and electroencephalography (EEG) findings of five children with FXS, who presented with SE as their initial seizure.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Adolescent
  • Age of Onset
  • Anticonvulsants / therapeutic use
  • Child, Preschool
  • Electroencephalography / statistics & numerical data*
  • Epilepsy, Rolandic / diagnosis
  • Epilepsy, Rolandic / drug therapy
  • Epilepsy, Rolandic / genetics
  • Female
  • Fragile X Syndrome / diagnosis*
  • Fragile X Syndrome / drug therapy
  • Fragile X Syndrome / genetics*
  • Genetic Predisposition to Disease / genetics
  • Humans
  • Intellectual Disability / diagnosis*
  • Intellectual Disability / genetics*
  • Magnetic Resonance Imaging
  • Male
  • Status Epilepticus / diagnosis*
  • Status Epilepticus / drug therapy
  • Status Epilepticus / genetics*
  • Syndrome

Substances

  • Anticonvulsants