In the mol-ecule of the title compound, C(17)H(15)N(5)O(3)S, the planar central heterocylic ring system is oriented at dihedral angles of 5.32 (4) and 9.41 (4)°, respectively with respect to trimethoxy-phenyl and pyridine rings. Intra-molecular C-H⋯N, C-H⋯O and C-H⋯S hydrogen bonds result in the formation of a nearly planar six-membered ring, which is oriented at a dihedral angle of 3.07 (5)° with respect to the central heterocylic ring system, and non-planar six- and five-membered rings having twist and envelope conformations, respectively. In the crystal structure, inter-molecular C-H⋯N and C-H⋯O hydrogen bonds link the mol-ecules. There is a C-H⋯π contact between the pyridine ring and a methyl group and a π-π contact between the central heterocylic ring system and the trimethoxy-phenyl ring [centroid-centroid distance = 3.758 (1) Å].