CTX-M-producing non-Typhi Salmonella spp. isolated from humans, United States

Emerg Infect Dis. 2011 Jan;17(1):97-9. doi: 10.3201/eid1701.100511.

Abstract

CTX-M-type beta-lactamases are increasing among US Enterobacteriaceae isolates. Of 2,165 non-Typhi Salmonella isolates submitted in 2007 to the National Antimicrobial Resistance Monitoring System, 100 (4.6%) displayed elevated MICs (≥2 mg/L) of ceftriaxone or ceftiofur. Three isolates (serotypes Typhimurium, Concord, and I 4,5,12:i:-) contained bla(CTX-M-5), bla(CTX-M-15), and bla(CTX-M-55/57), respectively.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Ceftriaxone / pharmacology
  • Cephalosporin Resistance
  • Cephalosporins / pharmacology
  • Humans
  • Infant
  • Microbial Sensitivity Tests
  • Population Surveillance / methods
  • Salmonella / classification
  • Salmonella / drug effects*
  • Salmonella / enzymology
  • Salmonella / isolation & purification
  • Salmonella Infections / epidemiology*
  • Salmonella Infections / microbiology
  • Salmonella typhimurium / drug effects*
  • Salmonella typhimurium / enzymology
  • Salmonella typhimurium / genetics
  • Salmonella typhimurium / isolation & purification
  • Serotyping
  • United States / epidemiology
  • beta-Lactam Resistance
  • beta-Lactamases / biosynthesis*
  • beta-Lactamases / genetics

Substances

  • Anti-Bacterial Agents
  • Cephalosporins
  • Ceftriaxone
  • ceftiofur
  • beta-lactamase CTX-M-15
  • beta-Lactamases