R132H-mutation of isocitrate dehydrogenase-1 is not sufficient for HIF-1α upregulation in adult glioma

Acta Neuropathol. 2011 Feb;121(2):279-81. doi: 10.1007/s00401-010-0790-y. Epub 2010 Dec 24.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Arginine / genetics*
  • Child
  • Child, Preschool
  • Female
  • Glioma / genetics*
  • Histidine / genetics*
  • Humans
  • Hypoxia-Inducible Factor 1, alpha Subunit / metabolism*
  • Infant
  • Isocitrate Dehydrogenase / genetics*
  • Male
  • Middle Aged
  • Mutation / genetics*
  • Up-Regulation / genetics*
  • Young Adult

Substances

  • HIF1A protein, human
  • Hypoxia-Inducible Factor 1, alpha Subunit
  • Histidine
  • Arginine
  • Isocitrate Dehydrogenase