Efficacy of out-hospital treatment of coagulation disorders in patients with diabetes mellitus type II (DMII) in comparison with non-diabetic patients after aortic-femoral reconstruction was studied. Long-term results were obtained within 65,1±3,95 months after surgery. Data of 67 patients were obtained, of them 32 had severe DMII, 35 patients had no diabetic disorders. 94% of patients had various hypercoagulation disorders and thrombophilia stage I-II. Desagregant therapy was noneffective in 70,1% of patients. Patients with atherosclerosis after reconstructive vascular surgery showed disorders of both thrombocytic and plasma links of coagulation, which requires combined (anticoagulant and desagregant) therapy. Patients with DMII require also blood glucose and HbA1c control postoperatively.