[Application df/dt(max) index for determinations of skeletal contractility]

Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2003 Nov;19(4):413-5.
[Article in Chinese]

Abstract

Aim: To analyze the most force rising ratio (+ dF/dt(max)) and the most force descending ratio (- dF/dt(max)) for more sensitive index of skeletal contractility.

Methods: Mouse model of swimming training was used, most force (f(max)), + dF/dt(max) and - dF/ dt(max) of gastrocnemius contracting were measured and changes of gastrocnemius supermicro-structure was observed.

Results: Mitochondria increased and myoneme was regular in general training load, gastrocnemius F(max) - dF/dt(max) significantly increased than in control (P < 0.05), + dF/dt(max) increased more significantly (P < 0.01). Mitochondria was rare and myoneme was unusual in overtraining load, gastrocnemius F(max), - dF/dt(max) reduced significantly than in control (P < 0.05), + dF/dt(max) reduced more significantly (P < 0.01).

Conclusion: + dF/dt(max) is better index than F(max) in judging skeletal contractility.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Female
  • Mice
  • Mice, Inbred BALB C
  • Muscle Contraction / physiology*
  • Muscle, Skeletal / physiology*
  • Muscle, Skeletal / ultrastructure
  • Swimming / physiology*