Uncovering new properties of imidazolium salts: Cl- transport and supramolecular regulation of their transmembrane activity

Claude-Rosny Elie; Nadim Noujeim; Christophe Pardin; Andreea R Schmitzer

doi:10.1039/c0cc04280c

Uncovering new properties of imidazolium salts: Cl- transport and supramolecular regulation of their transmembrane activity

Chem Commun (Camb). 2011 Feb 14;47(6):1788-90. doi: 10.1039/c0cc04280c. Epub 2010 Dec 3.

Authors

Claude-Rosny Elie¹, Nadim Noujeim, Christophe Pardin, Andreea R Schmitzer

Affiliation

¹ Department of Chemistry, Université de Montréal, 2900 Edouard Montpetit CP 6128 Succursalle Centre-ville, Montréal, Québec, Canada.

PMID: 21132159
DOI: 10.1039/c0cc04280c

Abstract

We report the Cl(-) transport activity for three imidazolium-based transporters. We present significant findings regarding the use of α-cyclodextrin and cucurbit[7]uril macrocycles to form inclusion complexes with these salts and to inhibit their membrane activity.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anions / chemistry
Anions / metabolism
Biological Transport
Bridged-Ring Compounds / chemistry
Bridged-Ring Compounds / metabolism
Buffers
Cell Membrane / chemistry
Cell Membrane / metabolism*
Cell Membrane Permeability
Chlorides / chemistry*
Chlorides / metabolism
Hydrogen-Ion Concentration
Imidazoles / chemistry
Imidazoles / metabolism
Imidazolines / chemistry*
Imidazolines / metabolism
Magnetic Resonance Spectroscopy
Salts / chemistry*
Salts / metabolism
Solutions / chemistry
alpha-Cyclodextrins / chemistry
alpha-Cyclodextrins / metabolism

Substances

Anions
Bridged-Ring Compounds
Buffers
Chlorides
Imidazoles
Imidazolines
Salts
Solutions
alpha-Cyclodextrins
cucurbit(7)uril
alpha-cyclodextrin