Two new flavonoid glycosides from the whole herbs of Hyssopus officinalis

J Asian Nat Prod Res. 2010 Dec;12(12):1044-50. doi: 10.1080/10286020.2010.533120.

Abstract

Two new flavonoid glycosides, quercetin 7-O-β-D-apiofuranosyl-(1 → 2)-β-D-xylopyranoside (1) and quercetin 7-O-β-D-apiofuranosyl-(1 → 2)-β-D-xylopyranoside 3'-O-β-D-glucopyranoside (2), together with nine known flavonoids were isolated from the whole herbs of Hyssopus officinalis L. cultivated in Xinjiang Uygur Autonomous Region of China. All structures were characterized by the spectroscopic methods including UV, IR, ESI-MS, 1D, and 2D NMR. Their potent free radical scavenging activity against the stable 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical was evaluated.

MeSH terms

  • Algorithms
  • Biphenyl Compounds / pharmacology
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Drugs, Chinese Herbal / pharmacology
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification*
  • Free Radical Scavengers / pharmacology
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Glycosides / pharmacology
  • Lamiaceae / chemistry*
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Picrates / pharmacology
  • Quercetin / analogs & derivatives*
  • Quercetin / chemistry
  • Quercetin / isolation & purification*
  • Quercetin / pharmacology
  • Stereoisomerism

Substances

  • Biphenyl Compounds
  • Drugs, Chinese Herbal
  • Free Radical Scavengers
  • Glycosides
  • Picrates
  • quercetin 7-O-beta-D-apiofuranosyl-(1-2)-beta-D-xylopyranoside
  • quercetin 7-O-beta-D-apiofuranosyl-(1-2)-beta-D-xylopyranoside 3'-O-beta-D-glucopyranoside
  • Quercetin
  • 1,1-diphenyl-2-picrylhydrazyl