The main objective of the current study was to investigate the dynamic mechanical properties of a room-temperature vulcanizing silicone incorporating different fractions of zinc oxide (ZnO) after indoor and outdoor photoaging. Forty-eight samples were produced by adding different amounts of ZnO into a commercial maxillofacial silicone (EPISIL-E). The samples were divided into 4 groups containing 0.0, 0.2, 0.5, and 1 wt% ZnO additive, respectively. Samples were exposed to sunlight (subgroup 2), ultraviolet (subgroup 3), and fluorescence (subgroup 4) aging, whereas nonaged samples comprised the control subgroup (subgroup 1). Dynamic mechanical analysis was used to determine the storage modulus (E'), loss modulus (E″), and damping capacity (tanδ). General linear statistic model was conducted to evaluate the effects of aging, testing frequency, and composition on the dynamic mechanical properties of the silicone with the ZnO additive. Post hoc analysis was performed using Tukey test. Statistical analysis revealed a significant impact of composition on tanδ (P < 0.05). Aging influenced E' and E″ (P < 0.01). The combination of aging and composition had a significant effect on all dynamic properties (P < 0.01).