Abstract
Members of the Curcuma plant species (Zingiberaceae) have been used for centuries in cooking, cosmetics, staining and in traditional medicine as "omnipotent" remedies. Herbal preparations made with, and molecules extracted from, Curcuma have been shown to possess a wide variety of pharmacological properties against malignant proliferation, hormonal disorders, inflammation, and parasitosis among other conditions. This review evaluates Curcuma and its associated bioactive compounds, particularly focusing on studies examining the parasiticidal activity of these components against the tropical parasites Plasmodium, leishmania, Trypanosoma, Schistosoma and more generally against other cosmopolitan parasites (nematodes, Babesia, Candida, Giardia, Coccidia and Sarcoptes).
© Georg Thieme Verlag KG Stuttgart · New York.
MeSH terms
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Animals
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Antiparasitic Agents / chemistry
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Antiparasitic Agents / pharmacology*
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Antiparasitic Agents / therapeutic use
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Babesiosis / drug therapy
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Babesiosis / parasitology
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Coccidiosis / drug therapy
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Coccidiosis / parasitology
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Curcuma / chemistry*
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Curcumin / chemistry
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Curcumin / pharmacology*
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Curcumin / therapeutic use
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Giardiasis / drug therapy
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Giardiasis / parasitology
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Helminthiasis / drug therapy
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Helminthiasis / parasitology
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Humans
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Leishmaniasis / drug therapy
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Leishmaniasis / parasitology
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Malaria / drug therapy
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Malaria / parasitology
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Parasites / drug effects*
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Parasites / pathogenicity
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Parasitic Diseases / drug therapy*
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Parasitic Diseases / parasitology
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Plant Preparations / chemistry
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Plant Preparations / pharmacology*
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Plant Preparations / therapeutic use
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Scabies / drug therapy
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Scabies / parasitology
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Schistosomiasis / drug therapy
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Schistosomiasis / parasitology
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Trypanosomiasis / drug therapy
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Trypanosomiasis / parasitology
Substances
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Antiparasitic Agents
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Plant Preparations
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Curcumin