Antithrombotic flavonoids from the faeces of Trogopterus xanthipes

Nat Prod Res. 2010 Nov;24(19):1843-9. doi: 10.1080/14786419.2010.482057.

Abstract

Chemical investigation of Trogopterus faeces has led to the isolation of seven flavonoids. Their structures were elucidated by chemical and spectral analyses. In an anticoagulative assay, three kaempferol coumaroyl rhamnosides had significant antithrombin activity. This is the first report on the occurrence of flavonoid glycosides in Trogopterus faeces.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anticoagulants / chemistry*
  • Anticoagulants / pharmacology*
  • Blood Coagulation / drug effects
  • Feces / chemistry*
  • Flavonoids / chemistry*
  • Flavonoids / pharmacology*
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Rabbits
  • Sciuridae

Substances

  • Anticoagulants
  • Flavonoids