Abstract
Fullerene hexakis-adducts bearing 12 peripheral mannose moieties have been prepared by grafting sugar derivatives onto the fullerene core and assayed as inhibitors of FimH, a bacterial adhesin, using isothermal titration calorimetry, surface plasmon resonance and hemagglutination assays.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adhesins, Escherichia coli / chemistry*
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Calorimetry
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Escherichia coli / metabolism*
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Fimbriae Proteins / chemistry*
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Fullerenes / chemistry*
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Hemagglutination Inhibition Tests
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Mannose / chemistry
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Surface Plasmon Resonance
Substances
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Adhesins, Escherichia coli
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Fullerenes
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fimH protein, E coli
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Fimbriae Proteins
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Mannose