[Intestinal lengthening using a gastric graft: experimental study in pigs]

Rev Col Bras Cir. 2010 Aug;37(4):284-7. doi: 10.1590/s0100-69912010000400009.
[Article in Portuguese]

Abstract

Objective: Novel experimental technique of intestinal lengthening with a gastric graft in swines is proposed.

Methods: Four male large white swines, weighing 15 to 20 kg and aging 50 to 60 days were underwent an intestinal lengthening using a gastric graft (Figure 1). Swines were re-operated to check the aspect of the lengthening surgery. At this time intestinal fragments of suture lines, respecting a 5 cm margin, were removed and sent to histological analysis.

Results: There wasn't any graft ischemia or necrosis, residual stomach was already dilated by the time of relaparotomies, regaining 50% of its original size. Only an intense atrophy of the gastric graft mucosa with no signs of necrosis at histological study (Figure 2).

Conclusion: Lengthening using a gastric graft is technically feasible, with viability of the graft. Studies with swines with SBS in a larger cohort will be necessary to analyze stomach graft function. In the future, this technique can be a bridge to intestinal transplantation.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Intestines / surgery*
  • Male
  • Stomach / transplantation*
  • Swine