Grand challenge commentary: Chemical transdifferentiation and regenerative medicine

Bridget K Wagner

doi:10.1038/nchembio.472

Grand challenge commentary: Chemical transdifferentiation and regenerative medicine

Nat Chem Biol. 2010 Dec;6(12):877-9. doi: 10.1038/nchembio.472.

Author

Bridget K Wagner¹

Affiliation

¹ Chemical Biology Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. bwagner@broadinstitute.org

PMID: 21079596
DOI: 10.1038/nchembio.472

Abstract

The ability to alter cell identity with small molecules represents a powerful approach to restore biological function lost because of cellular deficiency. Developing this capability through advances in chemical biology could have an enormous impact on human health.

MeSH terms

Animals
Cell Transdifferentiation / drug effects*
Cell Transdifferentiation / physiology
Chemistry / trends*
Diabetes Mellitus / drug therapy
Diabetes Mellitus / pathology
Humans
Recovery of Function
Regenerative Medicine / trends*
Signal Transduction / drug effects
Signal Transduction / physiology
Small Molecule Libraries

Substances

Small Molecule Libraries