AIDS-associated Penicillium marneffei infection of the central nervous system

Clin Infect Dis. 2010 Dec 15;51(12):1458-62. doi: 10.1086/657400. Epub 2010 Nov 5.

Abstract

Penicillium marneffei is an important human immunodeficiency virus-associated opportunistic infection endemic in Southeast Asia. Central nervous system infection has not been described. We report the first case series of 21 human immunodeficiency virus-infected patients who presented with a syndrome consistent with acute central nervous system infection and who had Penicillium marneffei isolated from cerebrospinal fluid.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • AIDS-Related Opportunistic Infections / diagnosis*
  • AIDS-Related Opportunistic Infections / microbiology*
  • Adult
  • Antifungal Agents / therapeutic use
  • Asia, Southeastern
  • Central Nervous System Fungal Infections / diagnosis*
  • Central Nervous System Fungal Infections / microbiology*
  • Cerebrospinal Fluid / microbiology
  • Female
  • Humans
  • Male
  • Penicillium / isolation & purification*
  • Treatment Outcome

Substances

  • Antifungal Agents