Abstract
The ability to utilize serum or plasma samples interchangeably is useful for tuberculosis (TB) serology. We demonstrate a strong correlation between antibody titers to several mycobacterial antigens in serum versus plasma from HIV-infected and non-HIV-infected TB and non-TB patients (r = 0.99 to 0.89; P < 0.0001). Plasma and serum can be used interchangeably in the same antibody detection assays.
Publication types
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Evaluation Study
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Antibodies, Bacterial / blood*
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Antigens, Bacterial / immunology*
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Bacterial Proteins / immunology
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Female
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HIV Infections / complications
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HIV Infections / immunology
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Humans
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Malate Synthase / immunology
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Male
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Mannans / immunology
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Middle Aged
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Mycobacterium bovis / immunology*
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Mycobacterium tuberculosis / immunology*
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Plasma / immunology*
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Serum / immunology*
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Tuberculosis / complications
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Tuberculosis / immunology
Substances
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Antibodies, Bacterial
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Antigens, Bacterial
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Bacterial Proteins
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MPT51 protein, Mycobacterium
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Mannans
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arabinomannan
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Malate Synthase