Germinoma of medulla

Neurol India. 2010 Sep-Oct;58(5):768-70. doi: 10.4103/0028-3886.72190.

Abstract

Germinoma occurring in the medulla oblongata is extremely rare. We report a case of primary intracranial germinoma arising in the medulla oblongata of a 24-year-old postpartum female who presented with progressive weakness of upper and lower limbs, seventh nerve palsy, and decreased palatal movements. Her MR imaging showed a heterointense mass lesion in the posterior portion of upper medulla, the histology of which was reported as germinoma. Germ cell tumors should be considered in the differential diagnosis of tumors occurring in the brain stem.

Publication types

  • Case Reports

MeSH terms

  • Alkaline Phosphatase / metabolism
  • Brain Stem Neoplasms / enzymology
  • Brain Stem Neoplasms / pathology*
  • Female
  • GPI-Linked Proteins / metabolism
  • Germinoma / enzymology
  • Germinoma / pathology*
  • Humans
  • Isoenzymes / metabolism
  • Magnetic Resonance Imaging / methods
  • Medulla Oblongata / enzymology
  • Medulla Oblongata / pathology*
  • Postpartum Period
  • Young Adult

Substances

  • GPI-Linked Proteins
  • Isoenzymes
  • Alkaline Phosphatase
  • alkaline phosphatase, placental