Mass spectrometry and renal calculi

J Med Life. 2010 Apr-Jun;3(2):128-36.

Abstract

The present review represents a concise and complete survey of the literature covering 2004-2009, concerning the mass spectrometric techniques involved in the structural investigation of renal calculi. After a short presentation of the fundamental mass spectrometric techniques (MALDI-TOF, QTOF, MS-MS) as well as hyphenated methods (GC-MS, LC-MS, CE-MS), an extensive study of the urinary proteome analysis as well as the detection and quantification by mass spectrometry of toxins, drugs and metabolites from renal calculi is presented.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Calcium Oxalate / analysis
  • Calcium Oxalate / urine
  • Chromatography, Liquid / methods
  • Electrophoresis, Capillary / methods
  • Food Contamination / analysis
  • Gas Chromatography-Mass Spectrometry / methods
  • Humans
  • Kidney Calculi / chemistry*
  • Kidney Calculi / urine
  • Mass Spectrometry / methods*
  • Osteopontin / urine
  • Proteome / analysis
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
  • Tandem Mass Spectrometry / methods
  • Triazines / toxicity
  • Triazines / urine

Substances

  • Proteome
  • Triazines
  • Osteopontin
  • Calcium Oxalate
  • melamine