Abstract
The present review represents a concise and complete survey of the literature covering 2004-2009, concerning the mass spectrometric techniques involved in the structural investigation of renal calculi. After a short presentation of the fundamental mass spectrometric techniques (MALDI-TOF, QTOF, MS-MS) as well as hyphenated methods (GC-MS, LC-MS, CE-MS), an extensive study of the urinary proteome analysis as well as the detection and quantification by mass spectrometry of toxins, drugs and metabolites from renal calculi is presented.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Calcium Oxalate / analysis
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Calcium Oxalate / urine
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Chromatography, Liquid / methods
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Electrophoresis, Capillary / methods
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Food Contamination / analysis
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Gas Chromatography-Mass Spectrometry / methods
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Humans
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Kidney Calculi / chemistry*
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Kidney Calculi / urine
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Mass Spectrometry / methods*
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Osteopontin / urine
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Proteome / analysis
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Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
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Tandem Mass Spectrometry / methods
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Triazines / toxicity
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Triazines / urine
Substances
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Proteome
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Triazines
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Osteopontin
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Calcium Oxalate
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melamine