Efficacy of induced luteinizing hormone surge after "trigger" with gonadotropin-releasing hormone agonist

Fertil Steril. 2011 Feb;95(2):826-8. doi: 10.1016/j.fertnstert.2010.09.009. Epub 2010 Oct 20.

Abstract

The magnitude of the LH surge after GnRH agonist "trigger" was correlated with oocyte yield and maturity and was suboptimal in approximately half of the cycles. A modest reduction in oocyte yield and maturity was observed when the serum level of LH 12 hours after GnRH agonist trigger was less than the median value (52 IU/L), and a dramatic reduction in yield and maturity was observed when that level was less than 12 IU/L.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Cell Count
  • Female
  • Fertility Agents, Female / pharmacology
  • Fertility Agents, Female / therapeutic use*
  • Gonadotropin-Releasing Hormone / agonists*
  • Humans
  • Infertility / blood
  • Infertility / pathology
  • Infertility / therapy*
  • Luteinizing Hormone / blood*
  • Oocyte Retrieval
  • Oocytes / cytology
  • Oocytes / pathology
  • Ovulation Induction / methods*
  • Retrospective Studies
  • Treatment Outcome
  • Up-Regulation / drug effects
  • Young Adult

Substances

  • Fertility Agents, Female
  • Gonadotropin-Releasing Hormone
  • Luteinizing Hormone