This cross-sectional research design compares the efficiency of videoconferencing in distance communication for signing deaf persons with that of teletypewriter (TTY)-based telecommunication for the deaf. The efficiency of message transmission was evaluated among 30 signing deaf persons (18 to 65 years) under the six following experimental conditions: (a) Omnitor Allan eC software, (b) Polycom ViaVideo II software, (c) Microsoft Windows Live Messenger software, (d) the D-Link videophone, (e) TTY (written French), and (f) face to face (reference standard). Three timed intelligibility tests and a satisfaction assessment were carried out for each of the experimental conditions. Results showed that videoconferencing technologies offer a better efficacy/time ratio for communication than does TTY. Communication using videoconferencing technologies was very similar to face-to-face communication; this was also true for technologies that are not designed specifically for the deaf population. Equivalent satisfaction levels were observed between TTY and videoconferencing technologies. Microsoft Windows Live Messenger was less preferred due to image fluidity issues.