Primary electrical diseases diagnosis, genetic and management

Minerva Cardioangiol. 2010 Aug;58(4):449-83.

Abstract

Primary electrical diseases or channelopathies are inherited genetic alterations of the cell ionic and electrical behavior leading to various cardiac arrhythmias carrying the risk of sudden death. A descriptive review of the successively described channelopathies is made in this article, with emphasis on the clinical manifestations, the genetic background and the currently accepted therapeutic options.

Publication types

  • Review

MeSH terms

  • Channelopathies / diagnosis*
  • Channelopathies / epidemiology
  • Channelopathies / genetics
  • Channelopathies / therapy*
  • Death, Sudden, Cardiac
  • Electrophysiology
  • Humans
  • Long QT Syndrome / diagnosis
  • Long QT Syndrome / genetics
  • Long QT Syndrome / therapy
  • Risk Assessment
  • Tachycardia, Ventricular / diagnosis
  • Tachycardia, Ventricular / genetics
  • Tachycardia, Ventricular / therapy
  • Ventricular Fibrillation / diagnosis
  • Ventricular Fibrillation / physiopathology
  • Ventricular Fibrillation / therapy