Abstract
Giant and functional paragangliomas of the skull base are rare. Their endocrinological and surgical management is challenging. We report the case of an aggressive giant noradrenalin-secreting paraganglioma of the right temporal bone. Three procedures of embolisation were performed. The second one was complicated by a hypertensive crisis due to catecholamine release. The tumour was resected via a widened transcochlear approach. Tumour residue was treated by gamma knife radiosurgery, without additional growth at the last follow-up. This case illustrates the interest of multidisciplinary management of giant skull base paragangliomas.
MeSH terms
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Contraindications
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Embolization, Therapeutic / adverse effects
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Embolization, Therapeutic / methods
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Humans
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Hypertension, Malignant / etiology
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Hypertension, Malignant / physiopathology
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Hypertension, Malignant / prevention & control
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Male
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Norepinephrine / metabolism
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Paraganglioma / metabolism
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Paraganglioma / pathology*
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Paraganglioma / therapy*
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Petrous Bone / diagnostic imaging
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Petrous Bone / pathology*
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Petrous Bone / surgery*
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Postoperative Complications / etiology
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Postoperative Complications / physiopathology
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Postoperative Complications / prevention & control
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Radiography
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Skull Base Neoplasms / metabolism
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Skull Base Neoplasms / pathology*
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Skull Base Neoplasms / therapy*
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Young Adult