Short-term in situ/ex vivo study of the anticariogenic potential of a resin-modified glass-ionomer cement associated with adhesive systems

Quintessence Int. 2010 Nov-Dec;41(10):e192-9.

Abstract

Objective: As resin-modified glass-ionomer cement (RMGIC) is an adhesive material, its association to dentin bonding agents (DBAs) was previously proposed. This study investigated the adjunctive behavior of an RMGIC with etch-and-rinse bonding systems under in situ/ex vivo cariogenic challenge.

Method and materials: Bovine enamel blocks (3 3 3 3 2 mm) were randomly assigned to group VP, Vitremer + its own primer (3M ESPE); group VSB, Vitremer + Single Bond (3M ESPE); and group VPB, Vitremer + Prime and Bond 2.1 (Dentsply). Two blocks of each group were randomly placed in an acrylic palatal appliance, so each appliance included six blocks. Volunteers (n = 10) wore these appliances according to given instructions to promote a sucrose challenge eight times/day for 15 days. After this period, the blocks were removed from the devices and cleaned, and demineralization was assessed through longitudinal microhardness analysis (Knoop indenter, 25 g/5 s). Data were submitted to three-way ANOVA and Tukey test (P < .05).

Results: No treatment was able to completely avoid demineralization. All materials showed a statistically significant difference in mineral loss when the microhardness on the outer enamel was compared with deeper regions (P < .05).

Conclusion: Association of the tested RMGICs with etch-and-rinse DBAs did not seem to be more beneficial against caries than the conventional treatment with RMGIC.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetone / adverse effects
  • Analysis of Variance
  • Animals
  • Bisphenol A-Glycidyl Methacrylate / adverse effects
  • Cariostatic Agents / therapeutic use*
  • Cattle
  • Composite Resins / therapeutic use
  • Cross-Sectional Studies
  • Dental Enamel
  • Dentin-Bonding Agents / adverse effects*
  • Drug Interactions
  • Glass Ionomer Cements / chemistry
  • Glass Ionomer Cements / therapeutic use*
  • Hardness
  • Humans
  • Polymethacrylic Acids / adverse effects
  • Resin Cements / adverse effects*
  • Statistics, Nonparametric
  • Tooth Demineralization / prevention & control*

Substances

  • Cariostatic Agents
  • Composite Resins
  • Dentin-Bonding Agents
  • Glass Ionomer Cements
  • Polymethacrylic Acids
  • Resin Cements
  • Vitremer
  • prime and bond 2.1
  • single bond
  • Acetone
  • Bisphenol A-Glycidyl Methacrylate