Predicting the consequences of cognitive impairment relative to day-to-day functioning is challenging, especially when impairment is mild. This study examined the ability of the Dementia Rating Scale (DRS) to predict Record of Independent Living (ROIL) performances in 2469 individuals with varying levels of cognitive ability, and describes specific activities of daily life that are likely impacted given specific DRS scores. Lower DRS scores were associated with greater difficulty in activities of daily living (ADLs), and effects of age, education, and gender were negligible. From a DRS total score, a corresponding ROIL score range and its specific associated impairments were determined. Functional impairments were noted even at mild levels of cognitive impairment. The DRS is helpful for determining the level of assistance that is likely needed in daily care and planning future care needs.