Esophegeal replacement in children with AIDS

J Pediatr Surg. 2010 Oct;45(10):2068-70. doi: 10.1016/j.jpedsurg.2010.06.026.

Abstract

We report 2 human immunodeficiency virus-positive patients with refractory esophageal strictures secondary to candidiasis. They presented with progressive dysphagia and had suffered from oropharyngeal and/or esophageal candidiasis within the preceding 3 months. Both failed conservative management of these strictures, including systemic antifungal therapy, administration of proton pump inhibitors, and numerous attempts at stricture dilation, ultimately progressing to open transhiatal esophagectomy. Although challenging in the immunocompromised host, successful treatment of these strictures by gastric interposition is achievable with minimal morbidity.

Publication types

  • Case Reports

MeSH terms

  • AIDS-Related Opportunistic Infections / complications
  • Acquired Immunodeficiency Syndrome / complications
  • Anastomosis, Surgical / methods
  • Candidiasis / complications
  • Catheterization / methods
  • Esophageal Stenosis / etiology
  • Esophageal Stenosis / surgery*
  • Esophagectomy / methods*
  • Esophagogastric Junction / surgery
  • Esophagoscopy
  • Esophagostomy / methods
  • Esophagus / surgery
  • Gastrostomy / methods
  • HIV Seropositivity
  • Humans
  • Infant
  • Male
  • Stomach / surgery*
  • Treatment Outcome