Aggregation properties of semisynthetic GM1 ganglioside (II3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety

Chem Phys Lipids. 1990 Nov;56(1):49-57. doi: 10.1016/0009-3084(90)90087-8.

Abstract

The aggregative properties of GM1 ganglioside containing an acetyl group as acyl moiety [GM1(acetyl)] in aqueous solution have been studied by static and dynamic light scattering measurements and surface tension experiments. GM1 (acetyl) spontaneously aggregates as small micelles showing a hydrodynamic radius and molecular weight of 34 A and 102 kDa, respectively, down to a concentration of 2.0 x 10(-5) M.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetylation
  • Carbohydrate Sequence
  • Chemical Phenomena
  • Chemistry, Physical
  • Chromatography, High Pressure Liquid
  • G(M1) Ganglioside / chemistry*
  • Light
  • Macromolecular Substances
  • Magnetic Resonance Spectroscopy
  • Micelles
  • Molecular Sequence Data
  • Molecular Weight
  • Scattering, Radiation
  • Surface Tension

Substances

  • Macromolecular Substances
  • Micelles
  • G(M1) Ganglioside