Emergence of fluoroquinolone-resistant Streptococcus pneumoniae in Lebanon: a report of three cases

Mazen R Naba; George F Araj; Tania A Baban; Zuhayr A Tabbarah; Ghassan N Awar; Souha S Kanj

doi:10.1016/j.jiph.2010.07.003

Emergence of fluoroquinolone-resistant Streptococcus pneumoniae in Lebanon: a report of three cases

J Infect Public Health. 2010;3(3):113-7. doi: 10.1016/j.jiph.2010.07.003. Epub 2010 Aug 24.

Authors

Mazen R Naba¹, George F Araj, Tania A Baban, Zuhayr A Tabbarah, Ghassan N Awar, Souha S Kanj

Affiliation

¹ Division of Infectious Diseases, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.

PMID: 20869671
DOI: 10.1016/j.jiph.2010.07.003

Abstract

The global emergence of Streptococcus pneumoniae resistance to fluoroquinolones is alarming and has grown to be a cause for significant concern worldwide. We report the first three cases of levofloxacin resistant S. pneumoniae isolates in a tertiary medical center in Beirut, Lebanon. Judicious use of antimicrobial agents is imperative to limit the spread of such resistant strains.

Publication types

Case Reports

MeSH terms

Aged
Anti-Bacterial Agents / pharmacology*
Anti-Bacterial Agents / therapeutic use*
Cefepime
Ceftazidime / pharmacology
Ceftazidime / therapeutic use
Cephalosporins / pharmacology
Cephalosporins / therapeutic use
Clarithromycin / pharmacology
Clarithromycin / therapeutic use
Drug Resistance, Multiple, Bacterial*
Humans
Imipenem / pharmacology
Imipenem / therapeutic use
Lebanon
Levofloxacin*
Male
Ofloxacin / pharmacology*
Ofloxacin / therapeutic use*
Pneumococcal Infections / drug therapy*
Pneumococcal Infections / microbiology
Pneumonia, Pneumococcal / drug therapy*
Pneumonia, Pneumococcal / microbiology
Streptococcus pneumoniae / drug effects*
Vancomycin / pharmacology
Vancomycin / therapeutic use

Substances

Anti-Bacterial Agents
Cephalosporins
Levofloxacin
Vancomycin
Imipenem
Cefepime
Ceftazidime
Ofloxacin
Clarithromycin