Abstract
Enantioselective catalysis in moderate to excellent yields and ee's has been accomplished using a phosphaalkene-based ligand system. Specifically, the palladium-catalyzed allylic alkylation of 1,3-diphenyl-2-propenyl acetate using a chiral P(sp(2)),N(sp(2)) ligand proceeds with a variety of malonate nucleophiles in 73-95% yield (79-92% ee).
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Alkenes / chemistry*
-
Alkylation
-
Allyl Compounds / chemistry*
-
Catalysis
-
Ligands
-
Models, Molecular
-
Molecular Structure
-
Oxazoles / chemistry*
-
Palladium / chemistry*
-
Phosphates / chemistry*
-
Stereoisomerism
Substances
-
Alkenes
-
Allyl Compounds
-
Ligands
-
Oxazoles
-
Phosphates
-
Palladium