Clinical and microbiological effects of mechanical instrumentation and local antimicrobials during periodontal supportive therapy in aggressive periodontitis patients: smoker versus non-smoker patients

J Clin Periodontol. 2010 Nov;37(11):998-1004. doi: 10.1111/j.1600-051X.2010.01623.x. Epub 2010 Sep 16.

Abstract

Aim: To compare the clinical and microbiological effects of ultrasonic mechanical instrumentation (UMI) associated to home-care use of amine fluoride/stannous fluoride (AmF/SnF(2) )-containing mouthrinse and toothpaste in smoker and non-smoker patients affected by generalized aggressive periodontitis (G-AgP) during a recall session of supportive periodontal therapy (SPT).

Material and methods: Thirteen smokers and 25 non-smokers G-AgP patients enrolled in an SPT programme received a single session of UMI associated with home-care use of AmF/SnF(2) -containing mouthrinse and toothpaste. Clinical and microbiological parameters were assessed pre-treatment, at 6 and 12 weeks post-treatment.

Results: In both groups, UMI plus AmF/SnF(2) -implemented oral hygiene use determined a significant decrease of total bacterial counts, with non-smokers exhibiting a lower count compared with smokers at 12 weeks. No significant differences were observed between smokers and non-smokers in the counts of total pathogens and red complex species at each observation interval. Clinically, a significant reduction of supragingival plaque, gingival inflammation and probing pocket depth was similarly observed in both groups.

Conclusions: A combined mechanical/chemical plaque control approach based on UMI and the use of AmF/SnF(2) agents resulted in the reduction of supragingival plaque deposits, gingival inflammation and subgingival periodontal pathogens in G-AgP patients during SPT, with no substantial difference between smokers and non-smokers.

Publication types

  • Comparative Study
  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aggressive Periodontitis / microbiology*
  • Aggressive Periodontitis / therapy*
  • Amines / therapeutic use
  • Anti-Infective Agents, Local / therapeutic use*
  • Colony Count, Microbial
  • Combined Modality Therapy
  • Dental Plaque / microbiology
  • Dental Scaling / methods*
  • Female
  • Fluorides, Topical / therapeutic use
  • Gingivitis / therapy
  • Humans
  • Male
  • Mouthwashes / chemistry
  • Mouthwashes / therapeutic use*
  • Periodontal Index
  • Smoking*
  • Sodium Fluoride / therapeutic use
  • Statistics, Nonparametric
  • Tin Fluorides / therapeutic use
  • Toothpastes / chemistry
  • Toothpastes / therapeutic use*
  • Ultrasonics

Substances

  • Amines
  • Anti-Infective Agents, Local
  • Fluorides, Topical
  • Mouthwashes
  • Tin Fluorides
  • Toothpastes
  • amine fluoride solution
  • amine fluoride gel
  • Sodium Fluoride