[Studies on the chemical constituents of Kalimeris indica]

Zhong Yao Cai. 2010 Apr;33(4):551-4.
[Article in Chinese]

Abstract

Objective: To study the chemical constituents from Kalimeris indica.

Methods: Compounds were isolated and purified with silica gel and Sephadex LH-20 column chromatography, their structures were determined by using spectroscopic analysis including MS and NMR.

Results: Nine compounds were isolated and identified as tritriacontane (I), hexadecanol (II), chrysophanol (III), vanillin (IV), physcion (V), beta-sitosterol (VI), stigmasterol (VII), leinoleic acid (VII), emodin (IX).

Conclusion: All of them, except compound IV, VI, are isolated from this genus for the first time. Compound III, IV had the protective effects with the toxicity of CCl4 on primary cultered hepatocytes.

MeSH terms

  • Anthraquinones / chemistry
  • Anthraquinones / isolation & purification
  • Anthraquinones / pharmacology
  • Anti-Inflammatory Agents / isolation & purification*
  • Anti-Inflammatory Agents / pharmacology
  • Asteraceae / chemistry*
  • Benzaldehydes / chemistry
  • Benzaldehydes / isolation & purification
  • Benzaldehydes / pharmacology
  • Carbon Tetrachloride
  • Cell Survival
  • Cells, Cultured
  • Chemical and Drug Induced Liver Injury
  • Emodin / analogs & derivatives
  • Emodin / chemistry
  • Emodin / isolation & purification
  • Emodin / pharmacology
  • Fatty Alcohols / chemistry
  • Fatty Alcohols / isolation & purification*
  • Fatty Alcohols / pharmacology
  • Hepatocytes / drug effects
  • Magnetic Resonance Spectroscopy
  • Paraffin / chemistry
  • Paraffin / isolation & purification*
  • Plants, Medicinal / chemistry*
  • Sitosterols / chemistry
  • Sitosterols / isolation & purification
  • Sitosterols / pharmacology

Substances

  • Anthraquinones
  • Anti-Inflammatory Agents
  • Benzaldehydes
  • Fatty Alcohols
  • Sitosterols
  • gamma-sitosterol
  • tritriacontane
  • Paraffin
  • vanillin
  • Carbon Tetrachloride
  • physcione
  • Emodin
  • chrysophanic acid