A new phenolic glycoside and cytotoxic constituents from Celosia argentea

J Asian Nat Prod Res. 2010 Sep;12(9):821-7. doi: 10.1080/10286020.2010.503652.

Abstract

A new phenolic glycoside, 4-O-β-D-apifuranosyl-(1→2)-β-D-glucopyranosyl-2-hydroxy-6-methoxyacetophenone (2) and 11 known compounds were isolated from the MeOH extract of the plant Celosia argentea. The structures of the compounds were elucidated on the basis of spectroscopic analysis and chemical methods. Among the isolated compounds, stigmasterol (10) showed moderate inhibitory activities against SGC-7901 and BEL-7404 cells.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / isolation & purification*
  • Antineoplastic Agents, Phytogenic / pharmacology*
  • Celosia / chemistry*
  • Drug Screening Assays, Antitumor
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Drugs, Chinese Herbal / pharmacology*
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Glycosides / pharmacology*
  • Humans
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Phenols / chemistry
  • Phenols / isolation & purification*
  • Phenols / pharmacology*
  • Stereoisomerism
  • Stigmasterol / pharmacology

Substances

  • 4-O-beta-D-apifuranosyl-(1-2)-beta-D-glucopyranosyl-2-hydroxy-6-methoxyacetophenone
  • Antineoplastic Agents, Phytogenic
  • Drugs, Chinese Herbal
  • Glycosides
  • Phenols
  • Stigmasterol