Antidiarrhoeal Activity of the Alcoholic Extract of the Leaves of Butea frondosa Koen. Ex Roxb

Indian J Pharm Sci. 2010 Mar;72(2):238-40. doi: 10.4103/0250-474X.65025.

Abstract

The study evaluated the antidiarrhoeal property of the alcohol extract of Butea frondosa leaf on mice and rats. Studies revealed that at a dose of 25 and 75 mg/kg a considerable reduction in the extent of diarrhoea was observed but at a dose of 100 mg/kg the animals appeared completely constipated when subjected to castor oil induced diarrhoea and intestinal motility model. Therefore, Butea frondosa can be regarded as an effective antidiarrhoeal.

Keywords: Butea frondosa; alcohol extract of the leaf; antidiarrhoeal; castor oil-induced diarrhea model.