Clinical features of a Dutch cohort of critically ill children due to the 2009 new influenza A H1N1 pandemic

Clin Pediatr (Phila). 2011 Jan;50(1):69-72. doi: 10.1177/0009922810381426. Epub 2010 Sep 13.

Abstract

Objective: This study describes the clinical course, treatment, and outcome of 13 critically ill children due to infection with new influenza A H1N1, admitted to 2 pediatric intensive care units (PICUs) in the northwestern part of the Netherlands.

Methods: Retrospective case series, conducted in 2 PICUs in Amsterdam, the Netherlands.

Results: A total of 13 children with a new influenza A H1N1 infection were admitted at 2 Dutch PICUs. The majority of these children were 12 to 16 years old and had an underlying disease. All children required mechanical ventilatory support. Shock was present in 7 of 13 (54%) children. Two children were transferred to a supraregional PICU with facilities for extracorporeal membrane oxygenation.

Conclusions: In a Dutch cohort of 13 critically ill children due to infection with new influenza (H1N1), respiratory (100%) and circulatory (54%) failure characterized the course of this infection in most of these children. All children survived.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Child
  • Critical Illness / therapy
  • Extracorporeal Membrane Oxygenation
  • Female
  • Humans
  • Influenza A Virus, H1N1 Subtype* / isolation & purification
  • Influenza, Human / complications*
  • Influenza, Human / diagnosis
  • Influenza, Human / therapy*
  • Influenza, Human / virology
  • Intensive Care Units, Pediatric
  • Male
  • Netherlands / epidemiology
  • Respiration, Artificial
  • Respiratory Insufficiency / therapy
  • Respiratory Insufficiency / virology
  • Retrospective Studies
  • Shock / therapy
  • Shock / virology
  • Treatment Outcome