The maternal and fetal impacts of obesity and gestational diabetes on pregnancy outcome

Best Pract Res Clin Endocrinol Metab. 2010 Aug;24(4):573-89. doi: 10.1016/j.beem.2010.06.001.

Abstract

Obesity has reached pandemic proportions and is of growing concern worldwide. Adverse health outcomes associated with a raised body mass index present the greatest challenge currently facing clinicians across all disciplines. Obesity is a chronic illness which is associated with metabolic disease, nutritional deficiency, musculoskeletal complications and cancer. These obesity-related health issues extend to pregnancy where they are responsible for producing a variety of medical and obstetric complications resulting in an increased incidence of maternal and fetal adverse outcomes. Management of diet, gestational diabetes and gestational and inter-gestational weight may improve outcomes in women who are obese during pregnancy. Specific recommendations for the management of obesity in pregnancy have recently been published.

Publication types

  • Review

MeSH terms

  • Bariatric Surgery
  • Body Mass Index
  • Diabetes Mellitus, Type 2 / etiology
  • Diabetes, Gestational / epidemiology
  • Diabetes, Gestational / physiopathology*
  • Female
  • Glucose Intolerance / etiology
  • Humans
  • Obesity / complications*
  • Obesity / therapy
  • Obstetric Labor Complications
  • Pregnancy / metabolism
  • Pregnancy Complications / etiology*
  • Pregnancy Outcome*
  • Weight Gain