Present paper provides first-hand information of certain ethnomedicinal plants from an Indo-Burma hotspot region (Mizoram, NE India). Forty ethnomedicinal plants recorded for the first time from this site of particular ecological relevance. Medical applications and conservation status of recorded plants have been described. In light of the fact that biodiversity characterization is now increasingly being recognized as an endangered field, such sort of biodiversity inventorying, monitoring, and assessment works are relevant particularly in relation to plants which are intimately linked with human welfare. Moreover, sustainable use of such components of biodiversity may extend important ecosystem services and also assist in their conservation.