Diagnostic value of the rapid influenza antigen test for novel influenza A (H1N1)

Scand J Infect Dis. 2011 Jan;43(1):43-6. doi: 10.3109/00365548.2010.508463. Epub 2010 Aug 25.

Abstract

We administered both the rapid antigen test and real-time reverse transcriptase polymerase chain reaction (RT-PCR) test to 2154 patients in order to assess the diagnostic value of the rapid antigen test during Korean pandemics of H1N1 2009. The overall sensitivity was 70.0%, specificity was 97.5%, positive predictive value was 97.4%, and negative predictive value was 71.2%. The sensitivity fell and the negative predictive value decreased as the RT-PCR positive rate increased.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antigens, Viral / analysis*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Immunoassay / methods
  • Infant
  • Infant, Newborn
  • Influenza A Virus, H1N1 Subtype / immunology
  • Influenza A Virus, H1N1 Subtype / isolation & purification*
  • Influenza, Human / diagnosis*
  • Korea
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • RNA, Viral / genetics
  • RNA, Viral / isolation & purification
  • Reverse Transcriptase Polymerase Chain Reaction / methods
  • Sensitivity and Specificity
  • Virology / methods*
  • Young Adult

Substances

  • Antigens, Viral
  • RNA, Viral