Strong intra- and inter-continental differentiation revealed by Y chromosome SNPs M269, U106 and U152

Fulvio Cruciani; Beniamino Trombetta; Cheyenne Antonelli; Roberto Pascone; Guido Valesini; Valentina Scalzi; Giuseppe Vona; Bela Melegh; Boris Zagradisnik; Guenter Assum; Georgi D Efremov; Daniele Sellitto; Rosaria Scozzari

doi:10.1016/j.fsigen.2010.07.006

Strong intra- and inter-continental differentiation revealed by Y chromosome SNPs M269, U106 and U152

Forensic Sci Int Genet. 2011 Jun;5(3):e49-52. doi: 10.1016/j.fsigen.2010.07.006. Epub 2010 Aug 22.

Authors

Fulvio Cruciani¹, Beniamino Trombetta, Cheyenne Antonelli, Roberto Pascone, Guido Valesini, Valentina Scalzi, Giuseppe Vona, Bela Melegh, Boris Zagradisnik, Guenter Assum, Georgi D Efremov, Daniele Sellitto, Rosaria Scozzari

Affiliation

¹ Dipartimento di Genetica e Biologia Molecolare, Sapienza Università di Roma, Rome, Italy.

PMID: 20732840
DOI: 10.1016/j.fsigen.2010.07.006

Abstract

More than 2700 unrelated individuals from Europe, northern Africa and western Asia were analyzed for the marker M269, which defines the Y chromosome haplogroup R1b1b2. A total of 593 subjects belonging to this haplogroup were identified and further analyzed for two SNPs, U106 and U152, which define haplogroups R1b1b2g and R1b1b2h, respectively. These haplogroups showed quite different frequency distribution patterns within Europe, with frequency peaks in northern Europe (R1b1b2g) and northern Italy/France (R1b1b2h).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chromosomes, Human, Y*
Haplotypes
Humans
Polymorphism, Single Nucleotide*