Epithelial pathways in choroid plexus electrolyte transport

Physiology (Bethesda). 2010 Aug;25(4):239-49. doi: 10.1152/physiol.00011.2010.

Abstract

A stable intraventricular milieu is crucial for maintaining normal neuronal function. The choroid plexus epithelium produces the cerebrospinal fluid and in doing so influences the chemical composition of the interstitial fluid of the brain. Here, we review the molecular pathways involved in transport of the electrolytes Na+, K+, Cl-, and HCO3(-)across the choroid plexus epithelium.

Publication types

  • Review

MeSH terms

  • Animals
  • Bicarbonates / metabolism
  • Carrier Proteins / metabolism
  • Cerebrospinal Fluid / metabolism
  • Chloride Channels / metabolism
  • Choroid Plexus / anatomy & histology
  • Choroid Plexus / metabolism
  • Choroid Plexus / physiology*
  • Epithelium / metabolism
  • Epithelium / physiology*
  • Humans
  • Potassium Channels / metabolism
  • Sodium Channels / physiology
  • Water / metabolism

Substances

  • Bicarbonates
  • Carrier Proteins
  • Chloride Channels
  • Potassium Channels
  • Sodium Channels
  • Water