Chiral sulfur derivatives in the allylation of acyl hydrazones: C(2)-symmetric bis-sulfinamides as enhanced chiral organic promoters

Org Biomol Chem. 2010 Oct 7;8(19):4388-93. doi: 10.1039/c0ob00078g. Epub 2010 Aug 6.

Abstract

Monosulfinamides and C(2)-symmetric bis-sulfinamides are convenient neutral chiral promoters in the allylation of acyl hydrazones, the nature of the spacer and the substituent at the sulfinyl sulfur are key elements for the enantioselectivity of the process.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Allyl Compounds / chemistry*
  • Amides / chemistry
  • Hydrazones / chemistry*
  • Molecular Structure
  • Stereoisomerism
  • Sulfur Compounds / chemistry*

Substances

  • Allyl Compounds
  • Amides
  • Hydrazones
  • Sulfur Compounds