The characterisation of mammalian tissue with 2D relaxation methods

Magn Reson Imaging. 2010 Sep;28(7):971-81. doi: 10.1016/j.mri.2010.03.015.

Abstract

The potential of two-dimensional (2D) relaxometry for characterising mammalian tissue is explored on samples of liver, kidney (cortex, medulla and ureter) as well as cartilage. Significant differences are found between the T(1)-T(2) spectra of healthy and diseased human cartilage which suggests that 2D relaxometry could have potential use in clinical diagnosis. The effect of reducing the recovery delay on the T(1)-T(2) spectrum is explored to try to identify the optimum balance between speed and accuracy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Animals
  • Biopolymers / analysis*
  • Biopolymers / chemistry*
  • Cattle
  • Liver / chemistry*
  • Magnetic Resonance Spectroscopy / methods*

Substances

  • Biopolymers