Introduction: To the best of our knowledge, soft tissue sarcomas have not prevously been reported as a complication during pregnancy.
Case presentation: A 28-year-old Caucasian woman was diagnosed with a transperitoneal sarcoma during pregnancy. Morphological, immunohistochemical, chromosomal and mutational analyses pointed towards a high-grade endometrial stromal sarcoma. Although surgery and chemotherapy are possible during pregnancy, we were unable to perform these in this case.
Conclusion: The potential to treat gynecological cancer during pregnancy should always be assessed individually.